Our Research

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Our scientists have been studying dog DNA for more than 20 years. But there’s always more to learn.

Making a difference. By testing your dog’s DNA with Wisdom Panel, you’re contributing to the largest veterinary genetic research study—ever. Each test brings us one step closer to the next scientific breakthrough in canine obesity, aging, or preventative care. In short, your results not only help you take better care of your pup but also empower us to improve the lives of the good-est boys and girls on earth for generations to come.

Wisdom Dog DNA

It’s a privilege to be part of the largest pet care company in the world. Below, discover the research fueling our dog DNA tests.

Wisdom Dog DNA

Recessive missense LAMP3 variant associated with defect in lamellar body biogenesis and fatal neonatal interstitial lung disease in dogs

PLOS Genetics, 03/09/2020

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Wisdom Dog DNA

A putative silencer variant in a spontaneous canine model of retinitis pigmentosa

PLOS Genetics, 03/09/2020

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Wisdom Dog DNA

Characterisation of canine KCNIP4: A novel gene for cerebellar ataxia identified by whole-genome sequencing two affected Norwegian Buhund dogs

PLOS Genetics, 1/30/2020

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Wisdom Dog DNA

True Colors: Commercially-acquired morphological genotypes reveal hidden allele variation among dog breeds, informing both trait ancestry and breed potential

PLOS One, 10/28/2019

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Wisdom Dog DNA

TSEN54 missense variant in Standard Schnauzers with leukodystrophy

PLOS One, 10/4/2019

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Wisdom Dog DNA

NME5 frameshift variant in Alaskan Malamutes with primary ciliary dyskinesia

PLOS Genetics, 9/3/2019

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Wisdom Dog DNA

Whole Genome Sequencing of Giant Schnauzer Dogs with Progressive Retinal Atrophy Establishes NECAP1 as a Novel Candidate Gene for Retinal Degeneration

MDPI Canine Genetics, 5/17/2019

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Wisdom Dog DNA

Canine models of human amelogenesis imperfecta: identification of novel recessive ENAM and ACP4 variants

Human Genetics, 03/15/2019

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Wisdom Dog DNA

Heterozygosity testing and multiplex DNA panel screening as a potential tool to monitor health and inbreeding in a small, closed dog population.

Canine Genetics and Epidemiology, 12/28/2018

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Wisdom Dog DNA

A novel KRT71 variant in curly‐coated dogs

Animal Genetics, 11/19/2018

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Wisdom Dog DNA

Origins and wanderings of the Finnish hunting spitzes

PLOS One, 6/29/2018

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Wisdom Dog DNA

Frequency and distribution of 152 genetic disease variants in over 100,000 mixed breed and purebred dogs.

PLOS Genetics, 4/30/2018

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Wisdom Dog DNA

Frequency of five disease-causing genetic mutations in a large mixed-breed dog population (2011–2012)

PLOS One, 11/22/2017

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Wisdom Dog DNA

An intronic LINE-1 insertion in MERTK is strongly associated with retinopathy in Swedish Vallhund dogs

PLOS One, 8/16/2017

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Wisdom Dog DNA

Founder representation and effective population size in old versus young breeds-genetic diversity of Finnish and Nordic Spitz.

Journal of Animal Breeding and Genetics, 3/10/2017

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Wisdom Dog DNA

Homozygous PPT1 Splice Donor Mutation in a Cane Corso Dog With Neuronal Ceroid Lipofuscinosis

Journal of Veterinary Internal Medicine, 12/23/2016

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Wisdom Dog DNA

An Inversion DisruptingFAM134B Is Associated with Sensory Neuropathy in the Border Collie Dog Breed

G3: Genes, Genomes, Genetics, 9/1/2016

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Wisdom Dog DNA

Genetic Panel Screening of Nearly 100 Mutations Reveals New Insights into the Breed Distribution of Risk Variants for Canine Hereditary Disorders

PLOS One, 8/15/2016

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Wisdom Dog DNA

A Novel Genome-Wide Association Study Approach Using Genotyping by Exome Sequencing Leads to the Identification of a Primary Open Angle Glaucoma Associated Inversion Disrupting ADAMTS17

PLOS One, 12/18/2015

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Wisdom Dog DNA

Two Independent Mutations in ADAMTS17 Are Associated with Primary Open Angle Glaucoma in the Basset Hound and Basset Fauve de Bretagne Breeds of Dog

PLOS One, 10/16/2015

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Wisdom Dog DNA

Genome Wide Analysis Indicates Genes for Basement Membrane and Cartilage Matrix Proteins as Candidates for Hip Dysplasia in Labrador Retrievers

PLOS One, 1/30/2014

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Wisdom Dog DNA

A web resource on DNA tests for canine and feline hereditary diseases

The Veterinary Journal, 8/1/2013

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Wisdom Dog DNA

Missense Mutation in CAPN1 Is Associated with Spinocerebellar Ataxia in the Parson Russell Terrier Dog Breed

PLOS One, 5/13/2013

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Wisdom Dog DNA

Genome-wide SNP and haplotype analyses reveal a rich history underlying dog domestication

Nature, 11/9/2012

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Wisdom Dog DNA

Parallel Mapping and Simultaneous Sequencing Reveals Deletions in BCAN and FAM83H Associated with Discrete Inherited Disorders in a Domestic Dog Breed

PLOS Genetics, 1/12/2012

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Wisdom Dog DNA

Complex population structure in African village dogs and its implications for inferring dog domestication history

Proceedings of the National Academy of Sciences of the United States of America, 8/3/2009

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Genetic Mapping of Fixed Phenotypes: Disease Frequency as a Breed Characteristic

Journal of Heredity, 3/25/2009

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Wisdom Dog DNA

Population Structure and Inbreeding From Pedigree Analysis of Purebred Dogs

Genetice, 8/1/2008

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Wisdom Dog DNA

Single-Nucleotide-Polymorphism-Based Association Mapping of Dog Stereotypes

Genetics, 6/1/2008

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Wisdom Dog DNA

A Single IGF1 Allele Is a Major Determinant of Small Size in Dogs

Science, 4/6/2007

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